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TMR Integrative Nursing  2017, Vol. 1 Issue (2): 12-20    DOI: 10.12032/TMRIN20171203
    
The effect of traditional Chinese medicine washing combined with massage for neonatal jaundice: a meta-analysis
Li Wang a, Ting Shuai b, Yun-Yun Wang a, Hong Cao c*
a Graduate College, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. b School and Hospital of Stomatology, Peking University, Beijing 100081, China. c Department of Osteoporosis Internal Medicine, Tianjin Hospital, Tianjin 300211, China.
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Abstract  Objective: To systematically assess the effect of traditional Chinese medicine washing (TCM washing) combined with massage for the treatment of neonatal jaundice.
Methods and analysis: Databases, including PubMed, the Cochrane Library, Embase, Web of Science, the Chinese Biomedical Literature Database (CBM), CNKI, and Wanfang Data were electronically searched for randomized controlled trials (from inception to July 2017). The methodological qualities of included trials were evaluated by the Cochrane risk of bias assessment tool. The meta-analysis was performed by using RevMan 5.3 software.
Results: Overall, thirteen trials with a total of 1998 participants were included. The results of meta-analysis indicated that TCM washing combined with massage group was significantly superior to the control group in the first meconium time (MD, -16.67; 95% CI, -24.59 to -8.74; P < 0.001), time for transformation of meconium (MD, -15.44; 95% CI, -23.59 to -7.28; P < 0.001), transcutaneous bilirubin index changes [after treating three days (MD, -1.99; 95% CI, -2.57 to -1.40; P < 0.001), after treating four days (MD, -1.86; 95% CI, -2.77 to -0.95; P < 0.001), after treating five days (MD, -2.44; 95% CI, -3.47 to -1.42; P < 0.001), after treating six days (MD, -2.23; 95% CI, -3.30 to -1.16; P < 0.001), and the changes of serum bilirubin levels [after treating five days (MD, -3.17; 95% CI, -5.83 to -0.50; P = 0.02), after treating six days (MD, -1.63; 95% CI, -3.10 to -0.16; P = 0.03), after treating fifteen days (MD,-1.20; 95% CI, -1.99 to -0.41; P = 0.003).
Conclusions: TCM washing combined with massage may be an effective therapy for the treatment of neonatal jaundice. It can accelerate the excretion of meconium, shorten the time for transformation of meconium, and decrease transcutaneous bilirubin index and the level of serum bilirubin. But it should be careful to interpreting these findings. Well-designed RCTs are needed to further clarify the conclusion.


Highlights  

Highlights
This meta-analysis systematically evaluated the efficacy of TCM washing combined with massage for neonatal jaundice, and showed TCM washing combined with massage can accelerate the excretion of meconium, shorten the time for transformation of meconium, and decrease transcutaneous bilirubin index and the level of serum bilirubin.

Key wordsTraditional Chinese medicine washing      Massage      Neonatal jaundice      Meta-analysis     
Published: 25 December 2017
Corresponding Authors: Hong Cao, Department of Osteoporosis Internal Medicine, Tianjin Hospital, NO. 406 Jiefang South Road, Hexi District, Tianjin 300211, China. Email: caohong1968@yeah.net.   
Cite this article:

Li Wang, Ting Shuai, Yun-Yun Wang, Hong Cao. The effect of traditional Chinese medicine washing combined with massage for neonatal jaundice: a meta-analysis. TMR Integrative Nursing, 2017, 1(2): 12-20.

URL:

http://www.tmrnursing.com/10.12032/TMRIN20171203     OR     http://www.tmrnursing.com/Y2017/V1/I2/12

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